Uncertainty created by the global crises of climate change, environmental degradation, and biodiversity loss creates anxiety and challenges one’s ability to feel hopeful and to act to mitigate or solve those crises. This paper aims to position positive, nonviolent interactions with wildlife as opportunities to build the active hope required to address those global crises. The impact of hope on personal and collective action will be integrated with the human mental and spiritual health benefits of connection with nature and wildlife. Sources include studies of anxiety and hope associated with climate change awareness, studies of the health benefits of time in nature, and studies that address wildlife management theory and practice. Although most historical wildlife interactions have been violent, wildlife management is shifting towards coexistence and opportunities for nonviolent engagement with wildlife are increasing. Such nonviolent encounters with wildlife can inspire individual and community actions which become hope-building practices themselves. If they are safe for both humans and wildlife, nonviolent wildlife interactions may be a hope-building practice that reduces anxiety and motivates action to address global environmental crises. These interactions should be considered in psychological and spiritual approaches to crisis-related anxiety. Also, wildlife interactions should be created by wildlife managers and environmental educators to encourage active involvement in addressing the climate, environmental, and biodiversity crises.